Revealing the selective mechanisms of inhibitors to PARP-1 and PARP-2 via multiple computational methods
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DOI: 10.7717/peerj.9241
Abstract: Background Research has shown that Poly-ADP-ribose polymerases 1 (PARP-1) is a potential therapeutic target in the clinical treatment of breast cancer. An increasing number of studies have focused on the development of highly selective inhibitors… read more here.
Keywords: revealing selective; mechanisms inhibitors; parp; inhibitors parp ... See more keywords