Highly Carbon-Selective Monofluoromethylation of β-Ketoesters with Fluoromethyl Iodide.
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DOI: 10.1021/acs.orglett.9b02175
Abstract: A highly carbon-selective monofluoromethylation of a broad range of β-ketoesters with fluoromethyl iodide under mild conditions is described. The uses of lithium tert-butoxide as the base and diglyme as the solvent made great contributions to… read more here.
Keywords: selective monofluoromethylation; carbon selective; ketoesters fluoromethyl; highly carbon ... See more keywords