Abstract 1598: RM-046, a first-in-class, mutant-selective, and oral KRASQ61H(ON) inhibitor that drives tumor regression in preclinical models and validates KRASQ61H as a therapeutic target
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DOI: 10.1158/1538-7445.am2023-1598
Abstract: KRASQ61H mutant cancers represent a significant unmet medical need and include common solid tumor histotypes such as non-small cell lung cancer (NSCLC), pancreatic ductal adenocarcinoma (PDAC), and colorectal cancer (CRC). Currently, there are no targeted… read more here.
Keywords: cancer; mutant; inhibitor; selective oral ... See more keywords
The Antimicrobial Efficacy Against Selective Oral Microbes, Antioxidant Activity and Preliminary Phytochemical Screening of Zingiber officinale
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DOI: 10.2147/idr.s364175
Abstract: Abstract Introduction Ginger (Zingiber officinale) has been one of the most commonly consumed herbal medicines for a long time to treat several common diseases. Antibacterial activity, antioxidant properties and many bioactive compounds in ginger have… read more here.
Keywords: antibacterial activity; zingiber officinale; selective oral; activity ... See more keywords