Discovery of Selective P2Y6R Antagonists with High Affinity and In Vivo Efficacy for Inflammatory Disease Therapy.
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DOI: 10.1021/acs.jmedchem.3c00210
Abstract: As a member of purinoceptors, the P2Y6 receptor (P2Y6R) plays a crucial role in modulating immune signals and has been considered as a potential therapeutic target for inflammatory diseases. On the basis of the speculated… read more here.
Keywords: compound; p2y6r; antagonists high; p2y6r antagonists ... See more keywords