COVID‐2019: The role of the nsp2 and nsp3 in its pathogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25719
Abstract: Last December 2019, a new virus, named novel Coronavirus (COVID‐2019) causing many cases of severe pneumonia was reported in Wuhan, China. The virus knowledge is limited and especially about COVID‐2019 pathogenesis. The Open Reading Frame… read more here.
Keywords: pathogenesis; covid 2019; covid; nsp2 nsp3 ... See more keywords
Emerging mutant populations of Listeria monocytogenes EGD-e under selective pressure of Thymbra capitata essential oil question its use in food preservation.
Sign Up to like & getrecommendations! Published in 2021 at "Food research international"
DOI: 10.1016/j.foodres.2021.110403
Abstract: Due to their excellent antimicrobial properties, essential oils (EO) have been proposed as potential preservatives for certain kinds of foods, such as dairy products. However, the occurrence of pathogenic populations that are resistant to EOs… read more here.
Keywords: pressure thymbra; populations listeria; monocytogenes egd; selective pressure ... See more keywords
Occurrence of CTX-M-15 and MCR-1-producing Enterobacterales in pigs, Portugal; evidences of direct links with antibiotic selective pressure.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2019.09.006
Abstract: BACKGROUND Our study aimed to prospectively analyze the occurrence of colistin-resistant and extended-spectrum ß-lactamase (ESBL)-producing Enterobacterales colonizing pigs in two farms in Portugal, and to evaluate the putative correlations with different antibiotic usages. MATERIAL AND… read more here.
Keywords: antibiotic selective; colistin; occurrence; producing enterobacterales ... See more keywords
Deciphering of microbial community and antibiotic resistance genes in activated sludge reactors under high selective pressure of different antibiotics.
Sign Up to like & getrecommendations! Published in 2019 at "Water research"
DOI: 10.1016/j.watres.2018.12.034
Abstract: Currently, the effects of high antibiotic concentrations on the performance of microbiota and antibiotic resistance genes (ARGs) in activated sludge (AS) process are not well characterized. Lab-scale batch reactors were performed to evaluate the dynamics… read more here.
Keywords: microbial community; community; antibiotic resistance; selective pressure ... See more keywords
PATH-47. TTF MAY APPLY SELECTIVE PRESSURE TO GLIOBLASTOMA CLONES WITH ANEUPLOIDY: A CASE REPORT
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.643
Abstract: The Tumor Treating Fields (TTF) mechanism of action is hypothesized act upon mitosis by disrupting the cell spindle apparatus. However, biomarkers and human tissue correlation of the effect of the TTF device are lacking. CASE:… read more here.
Keywords: ttf; ttf device; case; selective pressure ... See more keywords
Apparent Absence of Selective Pressure on Pneumocystis jirovecii Organisms in Patients with Prior Methotrexate Exposure
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00990-22
Abstract: Pneumocystis jirovecii infections occur in patients treated with methotrexate (MTX) because of immunosuppressive effects of this highly potent dihydrofolate reductase (DHFR) inhibitor. Conversely, MTX may act as an anti-P. jirovecii drug and consequently may exert… read more here.
Keywords: jirovecii; jirovecii organisms; pneumocystis jirovecii; selective pressure ... See more keywords
Selective pressure of fishways upon morphological and muscle enzymatic traits of migrating glass eels
Sign Up to like & getrecommendations! Published in 2017 at "Canadian Journal of Fisheries and Aquatic Sciences"
DOI: 10.1139/cjfas-2016-0110
Abstract: Fishways are built on obstacles to restore the connectivity between aquatic habitats. Our study investigated how species-specific fishways interact with interindividual trait differences among fish. We compared several groups of glass eels (Anguilla anguilla) climbing… read more here.
Keywords: glass eels; pressure fishways; glass; fishways upon ... See more keywords
The factors affecting the evolution of the anthocyanin biosynthesis pathway genes in monocot and dicot plant species
Sign Up to like & getrecommendations! Published in 2017 at "BMC Plant Biology"
DOI: 10.1186/s12870-017-1190-4
Abstract: BackgroundThe available data demonstrate that even in universal metabolic pathways, some species-specific regulatory features of structural genes are present. For instance, in the anthocyanin biosynthesis pathway (ABP), genes may be regulated by ABP-specific regulatory factors,… read more here.
Keywords: evolution; plant; plant species; selective pressure ... See more keywords
Evolution of H9N2 avian influenza virus in embryonated chicken eggs with or without homologous vaccine antibodies
Sign Up to like & getrecommendations! Published in 2018 at "BMC Veterinary Research"
DOI: 10.1186/s12917-018-1391-6
Abstract: BackgroundVaccines constitute a unique selective pressure, different from natural selection, drives the evolution of influenza virus. In this study, A/Chicken/Shanghai/F/1998 (H9N2) was continually passaged in specific pathogen-free embryonated chicken eggs with or without selective pressures… read more here.
Keywords: vaccine; selective pressure; influenza virus; virus ... See more keywords
Host circadian behaviors exert only weak selective pressure on the gut microbiome under stable conditions but are critical for recovery from antibiotic treatment
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3001865
Abstract: The circadian rhythms of hosts dictate an approximately 24 h transformation in the environment experienced by their gut microbiome. The consequences of this cyclic environment on the intestinal microbiota are barely understood and are likely… read more here.
Keywords: environment; selective pressure; gut microbiome; host ... See more keywords
PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.941666
Abstract: The two most common antibody targeting principles in oncology are the induction of direct antitumor effects and the release of antitumor T cell immunity by immune checkpoint blockade. These two principles, however, may be overlapping… read more here.
Keywords: oncology; cell; selective pressure; checkpoint ... See more keywords