Articles with "selective rsk" as a keyword



RiSKs in Computational Modeling of Isoform-Selective RSK Inhibitors

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Published in 2025 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.5c00951

Abstract: Recent developments around inhibitors of the 90 kDa ribosomal S6 serine/threonine kinases (RSK1-4) have been focused on the optimization of known pan-RSK inhibitors such as SL0101 and BI-D1870. The RSKs are an intriguing target for… read more here.

Keywords: computational modeling; selective rsk; isoform; rsk inhibitors ... See more keywords