Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer
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DOI: 10.1007/s10120-020-01094-0
Abstract: Background AT-rich interactive domain 1A ( ARID1A ) is a tumor suppressor gene that is frequently mutated in gastric cancer (GC). Although ARID1A mutations are not a druggable target for conventional treatments, novel therapeutic strategies… read more here.
Keywords: deficient; ezh2 inhibitors; arid1a deficient; cancer ... See more keywords