Discovery of Potent, Selective, and Short-Acting Peptidic V2 Receptor Agonists.
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DOI: 10.1021/acs.jmedchem.9b00132
Abstract: The vasopressin analogue desmopressin (desamino-d-arginine8 vasopressin, dDAVP, 1) is a potent vasopressin 2 (V2) receptor (V2R) agonist approved in many countries for the treatment of diabetes insipidus, primary nocturnal enuresis, nocturia, and coagulation disorders. Since… read more here.
Keywords: potent selective; selective short; acting peptidic; receptor ... See more keywords