Free-Radical-Promoted Site-Selective C-H Silylation of Arenes by Using Hydrosilanes.
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DOI: 10.1021/acs.orglett.7b02717
Abstract: A free-radical-promoted aryl/heteroaryl C-H silylation using hydrosilane was developed. This cross-dehydrogenative silylation enables both electron-rich and electron-poor aromatics to afford the desired arylsilanes in unique selectivity. A "para-selectivity" was observed by examination of over 54… read more here.
Keywords: silylation; selective silylation; site selective; free radical ... See more keywords
NBE-Controlled Palladium-Catalyzed Interannular Selective C-H Silylation: Access to Divergent Silicon-Containing 1,1'-Biaryl-2-Acetamides.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00690
Abstract: A novel palladium-catalyzed interannular selective C-H silylation of 1,1'-biaryl-2-acetamides is described. The combination of palladium catalyst with copper oxidant enables meta- or ortho-selective C-H silylation by employing hexamethyldisilane as a trimethylsilyl source, which relies on… read more here.
Keywords: selective silylation; palladium catalyzed; biaryl acetamides;