PdII-Catalyzed Site-selective β- and γ-C(sp3)-H Arylation of Primary Aldehydes Controlled by Transient Directing Groups.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c13586
Abstract: Pd(II)-catalyzed site-selective β- and γ-C(sp3)-H arylation of primary aldehydes is developed by rational design of L,X-type transient directing groups (TDG). External 2-pyridone ligands are identified to be crucial for the observed reactivity. By minimizing the… read more here.
Keywords: arylation primary; selective sp3; catalyzed site; sp3 arylation ... See more keywords
Pd-catalysed selective C(sp3)-H arylation and acetoxylation of alcohols.
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DOI: 10.1039/c9cc02911g
Abstract: A palladium catalyzed selective C(sp3)-H arylation and acetoxylation of alcohols using a practical bidentate auxiliary were developed. Masked alcohols were selectively arylated at the β-position with diverse aryl iodides for the first time. Moreover, an… read more here.
Keywords: sp3; acetoxylation; acetoxylation alcohols; arylation acetoxylation ... See more keywords
Electrochemical radical-mediated selective C(sp3)–S bond activation
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DOI: 10.1039/d2sc05507d
Abstract: Selective C(sp3)–S bond breaking and transformation remains a particularly important, yet challenging goal in synthetic chemistry. Over the past few decades, transition metal-catalyzed cross-coupling reactions through the cleavage of C(sp3)–S bonds provided a powerful platform… read more here.
Keywords: sp3 bond; sp3; selective sp3; sp3 bonds ... See more keywords
Heterogeneous Chitosan@copper Catalyzed Selective C(sp3)–H Sulfonylation of Ketone Hydrazones with Sodium Sulfinates: Direct Access to β-Ketosulfones
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DOI: 10.3390/catal13040726
Abstract: The exploration of inexpensive and stable heterogeneous catalysts for C–S coupling reactions remains a challenging issue. Herein, we successfully prepared a new biomass-derived copper catalyst and applied it to the selective C(sp3)–H-directed sulfonylation of ketone… read more here.
Keywords: copper; catalyst; sodium sulfinates; selective sp3 ... See more keywords