Flow reactor synthesis of unsymmetrically substituted p-terphenyls using sequentially selective Suzuki cross-coupling protocols
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DOI: 10.1080/17518253.2019.1677786
Abstract: ABSTRACT Synthetic procedures, based on integrated flow chemical methods, have been developed for the sequential chemo-selective Suzuki–Miyaura cross-coupling of 1,4-dibromo-2-nitrobenzene (1) with various arylboronic acids. The first Suzuki coupling step used a phosphine-(ligand)-free palladium catalyst… read more here.
Keywords: selective suzuki; cross coupling; unsymmetrically substituted;