Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression.
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DOI: 10.1021/acsmedchemlett.2c00481
Abstract: Wee1 is a tyrosine kinase that is highly expressed in several cancer types. Wee1 inhibition can lead to suppression of tumor cell proliferation and sensitization of cells to the effects of DNA-damaging agents. AZD1775 is… read more here.
Keywords: selective wee1; antitumor; myelosuppression; inhibitors led ... See more keywords