EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental cell"
DOI: 10.1016/j.devcel.2019.05.043
Abstract: Macropinocytosis has emerged as an important nutrient-scavenging pathway that supports tumor cell fitness. By internalizing extracellular protein and targeting it for lysosomal degradation, this endocytic pathway functions as an amino acid supply route, permitting tumor… read more here.
Keywords: egfr pak; macropinocytosis; pak signaling; signaling selectively ... See more keywords
PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29930-0
Abstract: Programmed death-1 (PD-1) and its ligand PD-L1 are checkpoint molecules which regulate immune responses. Little is known about their functions in T cell migration and there are contradictory data about their roles in regulatory T… read more here.
Keywords: regulates cell; selectively regulates; transendothelial migration; signaling selectively ... See more keywords