Selectively Tunable Synthesis of α-Trifluoromethyl Ketones.
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DOI: 10.1021/acs.orglett.3c00725
Abstract: A cross-coupling of aldehydes and α-trifluoromethyl alkyl bromides was developed via dual nickel/photoredox catalysis system. A wide variety of substrates bearing a diverse set of functional groups were compatible to afford α-trifluoromethyl ketones under very… read more here.
Keywords: synthesis trifluoromethyl; selectively tunable; trifluoromethyl ketones; tunable synthesis ... See more keywords