Selectivity within a Family of Bacterial Phosphothreonine Lyases.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00534
Abstract: Phosphothreonine lyases are bacterial effector proteins secreted into host cells to facilitate the infection process. This enzyme family catalyzes an irreversible elimination reaction that converts phosphothreonine or phosphoserine to dehydrobutyrine or dehydroalanine, respectively. Herein, we… read more here.
Keywords: phosphothreonine lyases; phosphothreonine; selectivity within; within family ... See more keywords
Exploring Subsite Selectivity within Plasmodium vivaxN-Myristoyltransferase Using Pyrazole-Derived Inhibitors
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.4c00168
Abstract: N-myristoyltransferase (NMT) is a promising antimalarial drug target. Despite biochemical similarities between Plasmodium vivax and human NMTs, our recent research demonstrated that high selectivity is achievable. Herein, we report PvNMT-inhibiting compounds aimed at identifying novel… read more here.
Keywords: exploring subsite; subsite selectivity; selectivity within; myristoyltransferase ... See more keywords
Exploration of Functional Group Effects on D2/H2 Separation Selectivity within the UiO-66 Framework
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic Chemistry Frontiers"
DOI: 10.1039/d4qi02802c
Abstract: The efficient separation of deuterium from hydrogen remains a significant challenge due to the limitations of convention-al techniques, such as cryogenic distillation and the Girdler-Sulfide process combined with electrolysis, which... read more here.
Keywords: exploration functional; effects separation; functional group; selectivity within ... See more keywords