Inhibition of Anaplerotic Glutaminolysis Underlies Selenite Toxicity in Human Lung Cancer
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DOI: 10.1002/pmic.201800486
Abstract: Large clinical trials and model systems studies suggest that the chemical form of selenium dictates chemopreventive and chemotherapeutic efficacy. Selenite induces excess ROS production, which mediates autophagy and eventual cell death in non‐small cell lung… read more here.
Keywords: cancer; glutaminolysis; selenite toxicity; lung cancer ... See more keywords