Novel Aurora A and Protein Kinase C (α, β1, β2, and θ) Multitarget Inhibitors: Impact of Selenium Atoms on the Potency and Selectivity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01031
Abstract: Aurora kinases and protein kinase C (PKC) have been shown to be involved in different aspects of cancer progression. To date, no dual Aurora/PKC inhibitor with clinical efficacy and low toxicity is available. Here, we… read more here.
Keywords: selenium; protein kinase; novel aurora; selectivity ... See more keywords
Selenium atoms induce organic doped systems to produce pure phosphorescence emission.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06380d
Abstract: A host-guest system is constructed using a guest containing two selenium atoms. The selenium atoms can increase the spin-orbit coupling constant and the conjugation degree, thereby increasing the emission wavelength, and making the materials show… read more here.
Keywords: induce organic; atoms induce; selenium atoms; selenium ... See more keywords
Effects of Selenium Atoms on [1]Benzochalcogenopheno[3,2-b][1]benzochalcogenophene-based Organic Semiconductors#
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry Letters"
DOI: 10.1246/cl.161020
Abstract: Effects of selenium substitution on [1]benzothieno[3,2-b][1]benzothiophene (BTBT) on transport properties were examined by comparison of 2,7-di-tert-butyl derivatives of BTBT and newly synthesized [1]benzoselenopheno[3,2-b][1]benzoselenophene (BSBS). The single-crystal field-effect transistors of the BSBS derivative showed slightly higher… read more here.
Keywords: selenium atoms; atoms benzochalcogenopheno; benzochalcogenopheno benzochalcogenophene; benzochalcogenophene based ... See more keywords