Articles with "selenolo pyrazine" as a keyword



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A convenient synthesis, reactions and biological evaluation of novel pyrazolo[3,4-b]selenolo[3,2-e]pyrazine heterocycles as potential anticancer and antimicrobial agents

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Published in 2020 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-020-02635-z

Abstract: A novel series of 5-amino-6-substituted-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]selenolo[3,2-e]pyrazines (3a–e) was synthesized by the reaction of the chloro pyrazolo[3,4-b]pyrazine carbonitrile 1 with selenium element in the presence of sodium borohydride and ethanol, followed by the reaction with α-halo alkylating… read more here.

Keywords: pyrazolo; selenolo pyrazine; synthesis; pyrazolo selenolo ... See more keywords