LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "selenoprotein" as a keyword



Photo by bermixstudio from unsplash

Site‐Specific Selenocysteine Incorporation into Proteins by Genetic Engineering

Sign Up to like & get
recommendations! Published in 2021 at "ChemBioChem"

DOI: 10.1002/cbic.202100124

Abstract: Selenocysteine (Sec), a rare naturally proteinogenic amino acid, is the major form of essential trace element selenium in living organisms. Selenoproteins, with one or several Sec residues, are found in all three domains of life.… read more here.

Keywords: selenocysteine incorporation; site specific; specific selenocysteine; incorporation ... See more keywords
Photo by slimmanny12 from unsplash

Selenoprotein N1 Redox Activity Leads to Mitochondrial Dysfunction in Skeletal Muscle

Sign Up to like & get
recommendations! Published in 2017 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2017.10.312

Abstract: Selenoprotein N (SEPN1), is a broadly expressed resident protein of the endoplasmic reticulum (ER) whose loss of function inexplicably leads to human muscle disease. We have defined the redox-regulated interactome of SEPN1 and identified the… read more here.

Keywords: skeletal muscle; sepn1; redox; selenoprotein ... See more keywords
Photo from wikipedia

Hepatic proteomic analysis of selenoprotein F knockout mice by iTRAQ: An implication for the roles of selenoprotein F in metabolism and diseases.

Sign Up to like & get
recommendations! Published in 2020 at "Journal of proteomics"

DOI: 10.1016/j.jprot.2020.103653

Abstract: Selenoprotein F (Selenof) is an endoplasmic reticulum (ER)-resident protein. It may be functionally linked to glycoprotein folding in the ER but the detail function is not fully understood. To study the function of Selenof, we… read more here.

Keywords: metabolism; selenof knockout; knockout mice; proteomic analysis ... See more keywords
Photo by sharonmccutcheon from unsplash

Elevated circulating Selenoprotein P levels in patients with polycystic ovary syndrome

Sign Up to like & get
recommendations! Published in 2021 at "Journal of Obstetrics and Gynaecology"

DOI: 10.1080/01443615.2021.1887112

Abstract: Abstract Selenoprotein P (SeP), an hepatokine that is primarily produced by liver, has been reported to affect glucose metabolism. In this study, we aimed to measure and compare serum SeP values in patients with polycystic… read more here.

Keywords: polycystic ovary; patients polycystic; selenoprotein; pcos ... See more keywords
Photo by chuttersnap from unsplash

SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation

Sign Up to like & get
recommendations! Published in 2017 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkx031

Abstract: Abstract Selenoprotein synthesis requires the co-translational recoding of a UGASec codon. This process involves an RNA structural element, called Selenocysteine Insertion Sequence (SECIS) and the SECIS binding protein 2 (SBP2). Several selenoprotein mRNAs undergo unusual… read more here.

Keywords: methylosome; smn complex; mrnp assembly; complex methylosome ... See more keywords
Photo by nci from unsplash

The selenoprotein P 3’ untranslated region is an RNA binding protein platform that fine tunes selenocysteine incorporation

Sign Up to like & get
recommendations! Published in 2022 at "PLoS ONE"

DOI: 10.1101/2020.11.23.394817

Abstract: Selenoproteins contain the 21st amino acid, selenocysteine (Sec), which is incorporated at select UGA codons when a specialized hairpin sequence, the Sec insertion sequence (SECIS) element, is present in the 3’ UTR. Aside from the… read more here.

Keywords: binding protein; rna binding; untranslated region; selenoprotein ... See more keywords
Photo by diabetesmagazijn from unsplash

Circulating selenoprotein P levels predict glucose‐lowering and insulinotropic effects of metformin, but not alogliptin: A post‐hoc analysis

Sign Up to like & get
recommendations! Published in 2022 at "Journal of Diabetes Investigation"

DOI: 10.1111/jdi.13949

Abstract: Selenoprotein P (SeP; encoded by SEPP1 in humans) is a hepatokine that causes impaired insulin secretion and insulin resistance. Metformin downregulates SELENOP promoter activity through an adenosine monophosphate‐activated kinase–forkhead box protein O3a pathway in hepatocytes. This study… read more here.

Keywords: circulating selenoprotein; predict glucose; selenoprotein; glucose lowering ... See more keywords