Effect of gemfibrozil and rifampicin on the pharmacokinetics of selexipag and its active metabolite in healthy subjects
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DOI: 10.1111/bcp.13379
Abstract: AIMS Based on in vitro data, there is evidence to suggest that cytochrome P450 (CYP) 2C8 is involved in the metabolism of selexipag and its active metabolite, ACT-333679. The present study evaluated the possible pharmacokinetic… read more here.
Keywords: act 333679; rifampicin; selexipag active; active metabolite ... See more keywords