Daily, limited access to methamphetamine self-administration during pregnancy leads to increased methamphetamine sensitivity in adult offspring.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental psychobiology"
DOI: 10.1002/dev.22350
Abstract: Methamphetamine use by women, even throughout pregnancy, is common. But there is limited knowledge about the effects in prenatally methamphetamine-exposed children. This study investigated how prenatal methamphetamine exposure in rats, via maternal i.v. self-administration, affected… read more here.
Keywords: self administration; methamphetamine; methamphetamine self; adult offspring ... See more keywords
Effect of self‐administration of medication programme on cardiovascular inpatients' medication adherence and nurses' satisfaction: A randomized clinical trial
Sign Up to like & getrecommendations! Published in 2021 at "Nursing Open"
DOI: 10.1002/nop2.870
Abstract: To investigate the effect of self‐administration of medication programme on medication adherence in cardiovascular inpatients and nurse's satisfaction. read more here.
Keywords: self administration; medication programme; medication adherence; medication ... See more keywords
Social context has differential effects on acquisition of nicotine self-administration in male and female rats
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4590-0
Abstract: RationalSmoking typically begins during adolescence or early adulthood in a social context, yet the role of social context in animal models is poorly understood.ObjectivesThe present study examined the effect of social context on acquisition of… read more here.
Keywords: self administration; context; acquisition nicotine; nicotine self ... See more keywords
Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4641-6
Abstract: Rationale and objectivesDesensitization of neuronal nicotinic acetylcholine receptors holds promise as an effective treatment of tobacco addiction. Previously, we found that sazetidine-A (Saz-A), which selectively desensitizes α4β2 nicotinic receptors, significantly decreased intravenous (IV) nicotine self-administration… read more here.
Keywords: self administration; administration; desensitizing agents; efficacies nicotinic ... See more keywords
Role of hypocretin/orexin receptor blockade on drug-taking and ultrasonic vocalizations (USVs) associated with low-effort self-administration of cathinone-derived 3,4-methylenedioxypyrovalerone (MDPV) in rats
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4709-3
Abstract: RationaleSynthetic psychostimulant abuse, including cathinone-derived 3,4-methylenedioxypyrovalerone (MDPV), continues to increase in many countries. Similar to cocaine but with greater potency, MDPV elicits a transient sympathomimetic response by blocking cellular uptake of dopamine (DA) and norepinephrine… read more here.
Keywords: self administration; drug; mdpv; drug taking ... See more keywords
Saccharin fading is not required for the acquisition of alcohol self-administration, and can alter the dynamics of cue-alcohol memory reconsolidation
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4824-1
Abstract: RationaleAnimal models of alcohol-seeking are useful for understanding alcohol addiction and for treatment development, but throughput in these models is limited by the extensive pretraining required to overcome the aversive taste of ethanol. Work by… read more here.
Keywords: self administration; administration; saccharin fading; nsf rats ... See more keywords
Intravenous cocaine self-administration in a panel of inbred mouse strains differing in acute locomotor sensitivity to cocaine
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-4834-7
Abstract: RationaleInitial sensitivity to drugs of abuse often predicts subsequent use and abuse, but this relationship is not always observed in human studies. Moreover, studies examining the relationship between initial locomotor sensitivity and the rewarding and… read more here.
Keywords: cocaine; self administration; administration; locomotor sensitivity ... See more keywords
Sex differences in incentive-sensitization produced by intermittent access cocaine self-administration
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5091-5
Abstract: RationaleIntermittent Access (IntA) cocaine self-administration, which models intermittent patterns of cocaine use in humans during the transition to addiction, is especially effective in producing incentive-sensitization and other addiction-like behavior in male rats. However, female rats… read more here.
Keywords: self administration; cocaine; incentive sensitization; sensitization ... See more keywords
Effects of chronic cocaine self-administration and N-acetylcysteine on learning, cognitive flexibility, and reinstatement in nonhuman primates
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-019-05211-5
Abstract: RationaleCocaine use disorder (CUD) is associated with cognitive deficits that have been linked to poor treatment outcomes. An improved understanding of cocaine’s deleterious effects on cognition may help optimize pharmacotherapies. Emerging evidence implicates abnormalities in… read more here.
Keywords: cocaine; self administration; cognitive flexibility; cocaine self ... See more keywords
Effects of methamphetamine isomers on d-methamphetamine self-administration and food-maintained responding in male rats
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DOI: 10.1007/s00213-019-05327-8
Abstract: Methamphetamine (METH) abuse is generally attributed to the d-isomer. Self-administration of l-METH has been examined only in rhesus monkeys with a history of cocaine self-administration or drug-naïve rats using high toxic doses. In this study,… read more here.
Keywords: self administration; administration; meth self; food maintained ... See more keywords
Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05489-w
Abstract: Rationale A variety of neural systems are involved in drug addiction, and some of these systems are shared across different addictive drugs. We have found several different types of drug treatments that successfully reduce nicotine… read more here.
Keywords: self administration; administration; amitifadine triple; remifentanil ... See more keywords