Efficient synthesis of 6-aryl-4-trifluoromethyl/ethoxycarbonyl-2 H -pyran-2-ones through self-condensation of penta-2,4-dienenitriles
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DOI: 10.1016/j.tetlet.2017.12.003
Abstract: Abstract An efficient synthesis of two new series of 6-aryl-4-trifluoromethyl-2H-pyran-2-ones and 6-aryl-4-carboxyethyl-2H-pyran-2-ones, obtained through the self-condensation reaction of 5-aryl-5-methoxy-3-(trifluoromethyl)penta-2,4-dienenitriles 3 and ethyl 4-aryl-2-(cyanomethylene)-4-methoxybut-3-enoates 4 respectively, is reported. The self-condensation reaction of the enoates 4 was… read more here.
Keywords: efficient synthesis; pyran ones; penta dienenitriles; self condensation ... See more keywords
Trifluoroacetic Acid-Mediated Oxidative Self-Condensation of Acetophenones in the Presence of SeO2: A Serendipitous Approach for the Synthesis of Fused [1,3]Dioxolo[4,5-d][1,3]dioxoles
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DOI: 10.1021/acsomega.1c01466
Abstract: A method for the synthesis of fused 1,3-dioxolanes was developed by self-condensation of glyoxal generated in situ by oxidation of acetophenones with SeO2 in the presence of trifluoroacetic acid. Three molecules of the glyoxal generated… read more here.
Keywords: synthesis fused; self condensation; trifluoroacetic acid; presence ... See more keywords