Self-diploidization of human haploid parthenogenetic embryos through the Rho pathway regulates endomitosis and failed cytokinesis
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DOI: 10.1038/s41598-017-04602-y
Abstract: A diploid genome is necessary for normal mammalian development, thus haploid parthenogenetic embryos undergo frequent self-diploidization during preimplantation development; however, the underlying mechanism is unclear. In this study, time-lapse recording revealed that human haploid parthenotes… read more here.
Keywords: self diploidization; embryos; rho pathway; hps ... See more keywords