The outer dynein arm assembly factor CCDC103 forms molecular scaffolds through multiple self‐interaction sites
Sign Up to like & getrecommendations! Published in 2019 at "Cytoskeleton"
DOI: 10.1002/cm.21591
Abstract: CCDC103 is a small protein with unusual biophysical properties that is required for outer dynein arm assembly on ciliary axonemes. Mutations in both human and zebrafish CCDC103 proteins lead to primary ciliary dyskinesia. Previous studies… read more here.
Keywords: arm assembly; interaction; outer dynein; ccdc103 ... See more keywords
Mapping the mAb Aggregation Propensity Using Self-Interaction Chromatography as a Screening Tool.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b04605
Abstract: The osmotic second virial coefficient ( B2), which describes protein-protein molecular interactions in solution, was determined using self-interaction chromatography (SIC) for an IgG1-type mAb across a wide range of solution conditions. These data were compared… read more here.
Keywords: chromatography; aggregation; interaction chromatography; using self ... See more keywords
Geometric description of self-interaction potential in symmetric protein complexes
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Data"
DOI: 10.1038/s41597-019-0058-x
Abstract: Proteins can self-associate with copies of themselves to form symmetric complexes called homomers. Homomers are widespread in all kingdoms of life and allow for unique geometric and functional properties, as reflected in viral capsids or… read more here.
Keywords: protein; potential symmetric; description self; interaction potential ... See more keywords
Single amino acid in V2 encoded by TYLCV is responsible for its self-interaction, aggregates and pathogenicity
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21446-2
Abstract: The V2 protein encoded by Begomovirus is essential for virus infection and is involved in multiple functions, such as virus movement and suppression of the host defence response. In this study, we reported that V2… read more here.
Keywords: amino acid; pathogenicity; interaction; encoded tylcv ... See more keywords
Use of Löwdin orthogonalised Fermi orbitals for self-interaction corrections in an iron porphyrin
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Physics"
DOI: 10.1080/00268976.2016.1225992
Abstract: ABSTRACT A new approach for formulating the self-interaction correction, referred to as the Fermi-Löwdin orbital-based self-interaction correction (FLO-SIC), is briefly reviewed and applied to the Fe(II)-porphyrin molecule. The Fermi–Löwdin orbitals are localised but due to… read more here.
Keywords: fermi wdin; porphyrin; self interaction; interaction correction ... See more keywords
High-throughput profiling of antibody self-association in multiple formulation conditions by PEG stabilized self-interaction nanoparticle spectroscopy
Sign Up to like & getrecommendations! Published in 2022 at "mAbs"
DOI: 10.1080/19420862.2022.2094750
Abstract: ABSTRACT Affinity-capture self-interaction nanoparticle spectroscopy (AC-SINS) is an assay developed to monitor the propensity of antibody self-association, hence assessing its colloidal stability. It has been widely used by pharmaceutical companies to screen antibodies at the… read more here.
Keywords: formulation; interaction nanoparticle; spectroscopy; self interaction ... See more keywords
Pivotal role of carbohydrate recognition domain in self-interaction of CLEC4A to elicit the ITIM-mediated inhibitory function in murine conventional dendritic cells in vitro.
Sign Up to like & getrecommendations! Published in 2020 at "International immunology"
DOI: 10.1093/intimm/dxaa034
Abstract: C-type lectin receptors (CLRs), pattern recognition receptors (PRRs) characteristic with a carbohydrate recognition domain (CRD) in the extracellular portion, mediate crucial cellular functions upon recognition of glycosylated pathogens and self-glycoproteins. CLEC4A is the only classical… read more here.
Keywords: interaction clec4a; clec4a; recognition; itim mediated ... See more keywords
Probing dark matter self-interaction with ultrafaint dwarf galaxies
Sign Up to like & getrecommendations! Published in 2021 at "Physical Review D"
DOI: 10.1103/physrevd.103.023017
Abstract: Self-interacting dark matter (SIDM) has gathered growing attention as a solution to the small-scale problems of the collisionless cold dark matter (CDM). We investigate the SIDM using stellar kinematics of the 23 ultra-faint dwarf (UFD)… read more here.
Keywords: dwarf; dark matter; self interaction; matter ... See more keywords
Kinetic Ising models with self-interaction: Sequential and parallel updating.
Sign Up to like & getrecommendations! Published in 2020 at "Physical review. E"
DOI: 10.1103/physreve.101.012122
Abstract: Kinetic Ising models on the square lattice with both nearest-neighbor interactions and self-interaction are studied for the cases of random sequential updating and parallel updating. The equilibrium phase diagrams and critical dynamics are studied using… read more here.
Keywords: parallel updating; self interaction; kinetic ising; ising models ... See more keywords
Many-Body Self-Interaction and Polarons.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review letters"
DOI: 10.1103/physrevlett.129.126401
Abstract: We address the many-body self-interaction in relation to polarons in density functional theory. Our study provides (i) a unified theoretical framework encompassing many-body and one-body forms of self-interaction and (ii) an efficient semilocal scheme for charge localization.… read more here.
Keywords: many body; body self; self interaction; interaction polarons ... See more keywords
The gravitational self-interaction of the Earth's tidal bulge
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Physics"
DOI: 10.1119/1.4985124
Abstract: According to a standard, idealized analysis, the Moon would produce a 54 cm equilibrium tidal bulge in the Earth's oceans. This analysis omits many factors (beyond the scope of the simple idealized model) that dramatically influence… read more here.
Keywords: tidal bulge; earth; gravitational self; bulge ... See more keywords