Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life
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DOI: 10.1098/rsos.170376
Abstract: In the RNA world hypothesis complex, self-replicating ribozymes were essential. For the emergence of an RNA world, less is known about the early processes that accounted for the formation of complex, long catalysts from small… read more here.
Keywords: trade offs; molecular trade; self ligation; trade ... See more keywords
Self-Ligation-Free Next Generation Sequencing Adapters Applied to Methylation Assay
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biomedical Nanotechnology"
DOI: 10.1166/jbn.2023.3518
Abstract: In developing a bisulfite-free methylation assay with the use of restriction enzymes, self-ligation of next generation sequencing adapters (NGS-adapter) is a technological bottleneck to be overcome. In the experiments of this study, a variety of… read more here.
Keywords: self ligation; methylation; methylation assay; next generation ... See more keywords