The role of Self Nano Emulsifying drug delivery systems of CDODA-Me in sensitizing Erlotinib resistant Nonsmall cell lung cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.01.010
Abstract: In this study we have investigated the effects of combination treatment involving ERL (Erlotinib) with a glycyrrhetinic acid analog, CDODA-Me in overcoming ERL resistance, and to improve the oral bioavailability of this treatment using self-Nano-emulsifying… read more here.
Keywords: combination; emulsifying drug; drug; self nano ... See more keywords
Solid self nano-emulsifying system for the enhancement of dissolution and bioavailability of Prasugrel HCl: in vitro and in vivo studies
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2021.1973495
Abstract: Abstract Prasugrel Hydrochloride (PHCl) is an antiplatelet drug. It is a class II drug with variable bioavailability. The objective of this work was to enhance the solubility and hence the bioavailability and efficacy of PHCl.… read more here.
Keywords: prasugrel; bioavailability; drug; self nano ... See more keywords
A14823 In vitro characterization and pharmacodynamic evaluation of furosemide loaded self nano emulsifying drug delivery systems (SNEDDS)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548312.49404.54
Abstract: Objectives: Poor water solubility is one of the reasons for erratic absorption after oral administration of furosemide (FSM), an antihypertensive loop diuretic. Self nano emulsifying drug delivery system (SNEDDS) is a novel drug delivery system… read more here.
Keywords: drug delivery; emulsifying drug; drug; self nano ... See more keywords
Improved Oral Pharmacokinetics of Pentoxifylline with Palm Oil and Capmul® MCM Containing Self-Nano-Emulsifying Drug Delivery System
Sign Up to like & getrecommendations! Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01644-w
Abstract: Pentoxifylline (PTX), an anti-hemorrhage drug used in the treatment of intermittent claudication, is extensively metabolized by the liver resulting in a reduction of the therapeutic levels within a short duration of time. Self-nano-emulsifying drug delivery… read more here.
Keywords: drug delivery; emulsifying drug; drug; self nano ... See more keywords
A SYSTEMATIC REVIEW ON SUPERSATURABLE SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEM: A POTENTIAL STRATEGY FOR DRUGS WITH POOR ORAL BIOAVAILABILITY
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2022v14i3.44178
Abstract: The most fundamental important extensive constitutive of drug molecules to be available for systemic absorption is aqueous solubility; subsequently, that is the nature of GIT fluid. When the drug molecules become solubilized, it has to… read more here.
Keywords: self nano; bioavailability; nano emulsifying; drug delivery ... See more keywords
Enhanced Antioxidant and Anti-Inflammatory Effects of Self-Nano and Microemulsifying Drug Delivery Systems Containing Curcumin
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DOI: 10.3390/molecules27196652
Abstract: Turmeric has been used for decades for its antioxidant and anti-inflammatory effect, which is due to an active ingredient isolated from the plant, called curcumin. However, the extremely poor water-solubility of curcumin often limits the… read more here.
Keywords: self nano; antioxidant anti; curcumin; anti inflammatory ... See more keywords
Enhancing Solubility and Bioavailability of Artemether and Lumefantrine through a Self-nano Emulsifying Drug Delivery System
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Pharmaceutical Sciences"
DOI: 10.36468/pharmaceutical-sciences.648
Abstract: In the present study artemether and lumefantrine self-nano emulsifying drug delivery system formulations were prepared using combination of these drugs with Capmul medical countermeasure, oleic acid and Tween 80. The particle size and zeta potential… read more here.
Keywords: delivery system; drug delivery; emulsifying drug; self nano ... See more keywords