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   Articles with "self nanoemulsifying" as a keyword



Enhancing biopharmaceutical performance of an anticancer drug by long chain PUFA based self‐nanoemulsifying lipidic nanomicellar systems

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recommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"

DOI: 10.1016/j.ejpb.2017.09.001

Abstract: Graphical abstract Figure. No Caption available. ABSTRACT The aim of this study was to develop polyunsaturated fatty acid (PUFA) long chain glyceride (LCG) enriched self‐nanoemulsifying lipidic nanomicelles systems (SNELS) for augmenting lymphatic uptake and enhancing… read more here.

Keywords: chain; biopharmaceutical performance; nanoemulsifying lipidic; long chain ... See more keywords

Solid self‐nanoemulsifying drug delivery systems for oral delivery of polypeptide‐k: Formulation, optimization, in‐vitro and in‐vivo antidiabetic evaluation

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recommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2017.08.022

Abstract: &NA; Development of self‐nanoemulsifying drug delivery systems (SNEDDS) of polypeptide‐k (PPK) is reported with the aim to achieve its oral delivery. Box‐Behnken design (BBD) was adopted to develop and optimize the composition of SNEDDS. Oleoyl… read more here.

Keywords: oral delivery; delivery; formulation; drug ... See more keywords

Evaluation of self‐nanoemulsifying drug delivery systems using multivariate methods to optimize permeability of captopril oral films

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recommendations! Published in 2019 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2019.01.039

Abstract: ABSTRACT The present report demonstrates a quality by design approach to understand and optimize self‐nanoemulsifying orodispersible films (SNEODF) of captopril for hypertension. A central composite experimental design was used to study the formulation parameters effects… read more here.

Keywords: tensile strength; young moduli; permeability; drug ... See more keywords
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Higher oral efficacy of ravuconazole in self-nanoemulsifying systems in shorter treatment in experimental chagas disease.

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recommendations! Published in 2021 at "Experimental parasitology"

DOI: 10.1016/j.exppara.2021.108142

Abstract: We investigated the in vitro activity and selectivity and in vivo efficacy of ravuconazole (RAV) in self-nanoemulsifying delivery system (SNEDDS) against Trypanosoma cruzi. Novel formulations of this poorly soluble C14-α-demethylase inhibitor may improve its efficacy… read more here.

Keywords: efficacy ravuconazole; treatment; efficacy; cure ... See more keywords

Formulation and biopharmaceutical evaluation of supersaturatable self‐nanoemulsifying drug delivery systems containing silymarin

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recommendations! Published in 2019 at "International Journal of Pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.11.036

Abstract: Graphical abstract Figure. No caption available. Abstract The first objective of this study was to optimize a supersaturatable self‐nanoemulsifying drug delivery system (S‐SNEDDS) containing silymarin through the investigation of the single and synergistic effect of… read more here.

Keywords: silymarin; nanoemulsifying drug; drug delivery; containing silymarin ... See more keywords

Self-Nanoemulsifying Drug Delivery System Combined with a Polymeric Amorphous System of Glibenclamide for Enhanced Drug Dissolution and Stability

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recommendations! Published in 2024 at "ACS Omega"

DOI: 10.1021/acsomega.4c07285

Abstract: Self-nanoemulsifying drug delivery systems (SNEDDS) have been widely applied to improve the dissolution and bioavailability of hydrophobic medications like glibenclamide (GB). However, the acid liability of GB limits its loading in SNEDDS formulation owing to… read more here.

Keywords: system; stability; self nanoemulsifying; dissolution ... See more keywords

Enhancing solubility and dissolution of felodipine using self-nanoemulsifying drug systems through in vitro evaluation

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-90962-9

Abstract: The main objective of the present study was to improve the solubility and dissolution rate of felodipine (FLD), a drug that does not dissolve well in water, using a self-nanoemulsifying drug delivery system (SNEDDS). Many… read more here.

Keywords: solubility dissolution; self nanoemulsifying; using self; dissolution ... See more keywords

Development and characterization of exendin-4 loaded self-nanoemulsifying system and in vitro evaluation on Caco-2 cell line

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recommendations! Published in 2019 at "Journal of Microencapsulation"

DOI: 10.1080/02652048.2019.1692945

Abstract: Abstract Aim: Aim of this study was to develop exendin-4 and exendin-4/chymostatin loaded self-nanoemulsifying drug delivery system (SNEDDS). Methods: Surfactants and co-surfactants were mixed, oil phase containing exendin-4 or exendin-4/chymostatin was added dropwise for SNEDDS.… read more here.

Keywords: loaded self; exendin; exendin loaded; exendin chymostatin ... See more keywords

Self-nanoemulsifying drug delivery systems (SNEDDS) of anti-cancer drugs: a multifaceted nanoplatform for the enhancement of oral bioavailability

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recommendations! Published in 2023 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2023.2182124

Abstract: Abstract Objective A significant problem faced by the health care industry today is that though there are numerous drugs available to tackle diseases like cancer, their intrinsic properties make it difficult to be delivered to… read more here.

Keywords: self nanoemulsifying; nanotechnology; drug delivery; drug ... See more keywords

A comprehensive study of the basic formulation of supersaturated self-nanoemulsifying drug delivery systems (SNEDDS) of albendazolum

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recommendations! Published in 2021 at "Drug Delivery"

DOI: 10.1080/10717544.2021.1986601

Abstract: Abstract Albendazolum (ABZ) is a BCS class II drug. It has challenging biopharmaceutical properties, which include poor solubility and dissolution rate. These properties have laid the ground for developing a supersaturated self-nanoemulsifying drug delivery system… read more here.

Keywords: supersaturated self; nanoemulsifying drug; drug delivery; drug ... See more keywords

Enhanced dissolution and bioavailability of revaprazan using self-nanoemulsifying drug delivery system

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recommendations! Published in 2022 at "Pharmaceutical Development and Technology"

DOI: 10.1080/10837450.2022.2070644

Abstract: Abstract A self-nanoemulsifying drug delivery system (SNEDDS) was developed to enhance the dissolution and oral bioavailability (BA) of revaprazan (RVP). Various SNEDDSs containing 200 mg of RVP were formulated using Capmul MCM, Tween 80, and Brij… read more here.

Keywords: self nanoemulsifying; dissolution; bioavailability revaprazan; delivery system ... See more keywords