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Published in 2017 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2017.02.011
Abstract: Background & Aims Three-dimensional organoid culture has fundamentally changed the in vitro study of intestinal biology enabling novel assays; however, its use is limited because of an inaccessible luminal compartment and challenges to data gathering…
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Keywords:
self renewing;
monolayer;
monolayer primary;
renewing monolayer ... See more keywords
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Published in 2020 at "Developmental biology"
DOI: 10.1016/j.ydbio.2020.02.007
Abstract: In amniotes, unlike primary neurulation in the anterior body, secondary neurulation (SN) proceeds along with axial elongation by the mesenchymal-to-epithelial transition of SN precursors in the tail bud. It has been under debate whether the…
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Keywords:
neurulation;
self renewing;
uni fated;
tail bud ... See more keywords
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Published in 2020 at "Cell death discovery"
DOI: 10.1038/s41420-020-00300-3
Abstract: Recent studies have revealed that tissue macrophages are derived from yolk sac precursors or fetal liver monocytes, in addition to bone marrow monocytes. The relative contribution of these cells to the tissue macrophage pool is…
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Keywords:
renewing macrophages;
self renewing;
bone marrow;
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Published in 2020 at "Nature Protocols"
DOI: 10.1038/s41596-020-00419-8
Abstract: The large intestine, with its array of crypts lining the epithelium and diverse luminal contents, regulates homeostasis throughout the body. In vitro crypts formed from primary human intestinal epithelial stem cells on a 3D shaped…
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Keywords:
collagen;
self renewing;
vitro generation;
human intestinal ... See more keywords
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Published in 2018 at "IEEE Transactions on Very Large Scale Integration (VLSI) Systems"
DOI: 10.1109/tvlsi.2018.2844463
Abstract: A recent surge of research on deep convolutional neural network (DCNN) has given a challenge on existing computation architecture which has the flows in speed and memory bottleneck. In the pretreatment of deep learning, mask…
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Keywords:
mask;
srmc multibit;
memory;
self renewing ... See more keywords
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Published in 2018 at "Journal of Immunology Research"
DOI: 10.1155/2018/4807145
Abstract: The immunologic interaction between parenchyma cells and encircling inflammatory cells is thought to be the most important mechanism of biliary damage and repair in primary sclerosing cholangitis (PSC). Monocytes/macrophages as master regulators of hepatic inflammation…
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Keywords:
notch signalling;
self renewing;
hpc;
expression ... See more keywords
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Published in 2022 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-22-0524
Abstract: Treatment with immune checkpoint blockade (ICB) often fails to elicit durable antitumor immunity. Recent studies suggest that ICB does not restore potency to terminally dysfunctional T cells, but instead drives proliferation and differentiation of self-renewing…
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Keywords:
cell;
icb;
self renewing;
blood ... See more keywords
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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.828086
Abstract: DOT1L is essential for embryonic hematopoiesis but the precise mechanisms of its action remain unclear. The only recognized function of DOT1L is histone H3 lysine 79 (H3K79) methylation, which has been implicated in both transcriptional…
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Keywords:
dot1l mediated;
self renewing;
dot1l;
extensively self ... See more keywords