DNA methylation testing for endometrial cancer detection in urine, cervicovaginal self‐samples and cervical scrapes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34504
Abstract: Endometrial cancer incidence is rising and current diagnostics often require invasive biopsy procedures. DNA methylation marker analysis of minimally‐ and non‐invasive sample types could provide an easy‐to‐apply and patient‐friendly alternative to determine cancer risk. Here,… read more here.
Keywords: endometrial cancer; dna methylation; self samples; cancer detection ... See more keywords
Increased HPV detection by the use of a pre-heating step on vaginal self-samples analysed by Aptima HPV assay.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2019.04.015
Abstract: BACKGROUND We recently reported a sensitivity of 85.5% to detect high-grade squamous intraepithelial lesions (HSIL)/adenocarcinoma in situ (AIS)/cancer by the use of self-collected vaginal samples analysed by the Aptima mRNA HPV assay (AHPV). OBJECTIVES To… read more here.
Keywords: heating step; self samples; ahpv positive; self ... See more keywords
Evaluation of p16INK4a immunocytology and human papillomavirus (HPV) genotyping triage after primary HPV cervical cancer screening on self-samples in China.
Sign Up to like & getrecommendations! Published in 2021 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2021.05.014
Abstract: OBJECTIVE Self-sampling for human papillomavirus (HPV) testing is an effective option to increase the cervical screening coverage. How to best triage HPV-positive self-samples remains controversial. Here, we evaluated the performance of a novel p16INK4a immunocytology… read more here.
Keywords: self samples; p16; hpv; hpv positive ... See more keywords
Clinical Performance of the RealTime High Risk HPV Assay on Self-Collected Vaginal Samples within the VALHUDES Framework
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01631-22
Abstract: Self-samples are becoming a crucial part of HPV-based cervical cancer screening programs to reach nonattendee women and increase screening coverage. Therefore, the VALHUDES framework was established to validate and evaluate HPV tests and devices on… read more here.
Keywords: valhudes framework; realtime high; high risk; risk hpv ... See more keywords
Cervical cancer screening using HPV tests on self-samples: attitudes and preferences of women participating in the VALHUDES study
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Public Health"
DOI: 10.1186/s13690-021-00667-4
Abstract: Background Interventions to reach women who do not participate regularly in screening may reduce the risk of cervical cancer. Self-collection of a vaginal specimen has been shown to increase participation. The relative clinical accuracy of… read more here.
Keywords: collection; self sampling; cervical cancer; self samples ... See more keywords