Self-structure assembly in single stranded polyriboadenylic acid by benzophenanthridine alkaloid: Spectroscopic and calorimetric exploration.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.08.119
Abstract: Present study allows us a better understanding of the interaction of nitidine, a benzophenanthridine alkaloid with single stranded polyriboadenylic acid [ss-poly (rA)]. The interaction leads to self-structure induction in ss-poly (rA) under the experimental condition… read more here.
Keywords: single stranded; benzophenanthridine alkaloid; stranded polyriboadenylic; polyriboadenylic acid ... See more keywords
Small molecule induced poly(A) single strand to self-structure conformational switching: evidence for the prominent role of H-bonding interactions.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00031f
Abstract: All messenger RNAs (mRNAs) have a polyadenylic acid tail that is added during post transcriptional RNA processing. Investigation of the structure-function and interactions of polyadenylic acid is an important area to target for cancer and… read more here.
Keywords: small molecule; poly; bonding interactions; structure ... See more keywords