How GRAIL controls Treg function to maintain self-tolerance
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DOI: 10.3389/fimmu.2022.1046631
Abstract: Regulatory T cells (Tregs) normally maintain self-tolerance. Tregs recognize “self” such that when they are not working properly, such as in autoimmunity, the immune system can attack and destroy one’s own tissues. Current therapies for… read more here.
Keywords: function; treg function; grail; drug ... See more keywords
The regulation of self-tolerance and the role of inflammasome molecules
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1154552
Abstract: Inflammasome molecules make up a family of receptors that typically function to initiate a proinflammatory response upon infection by microbial pathogens. Dysregulation of inflammasome activity has been linked to unwanted chronic inflammation, which has also… read more here.
Keywords: tolerance role; regulation self; inflammasome molecules; role inflammasome ... See more keywords