SCFFBXO28-mediated self-ubiquitination of FBXO28 promotes its degradation.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2019.109440
Abstract: The F-box protein is the substrate recognition subunit of SCF (SKP1/CUL1/F-box) E3 ubiquitin ligase complex, a multicomponent RING-type E3 ligase involved in the regulation of numerous cellular processes by targeting critical regulatory proteins for ubiquitination.… read more here.
Keywords: degradation; scf; self ubiquitination; box ... See more keywords
Chordate PIAS proteins act as conserved repressors of the TRAF6 self-polyubiquitination.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2019.103554
Abstract: In mammals, PIAS proteins are important SUMO E3 ligases and act as versatile regulators of over sixty different proteins, including components from the NF-κB pathways. But the PIAS functions are not well-understood due to complicated… read more here.
Keywords: pias proteins; chordate; traf6 self; self ubiquitination ... See more keywords