LAUSR

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.

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0 Published in 2018 at "Genome research"

DOI: 10.1101/gr.239186.118

Abstract: Mosaic mutations present in the germline have important implications for reproductive risk and disease transmission. We previously demonstrated a phenomenon occurring in the male germline, whereby specific mutations arising spontaneously in stem cells (spermatogonia) lead… read more here.

Keywords: mutations dysregulating; dysregulating ras; selfish mutations; selection ... See more keywords