Innovative evaluation of selinexor and JQ1 synergy in leukemia therapy via C-MYC inhibition
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DOI: 10.1186/s12967-025-06525-z
Abstract: Acute myeloid leukemia (AML) remains a therapeutic challenge due to drug resistance and relapse. Selinexor, an XPO1 inhibitor, shows limited efficacy as monotherapy, necessitating combination strategies. JQ1, a BET inhibitor targeting MYC, may synergize with… read more here.
Keywords: selinexor jq1; leukemia; jq1; myc inhibition ... See more keywords