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   Articles with "sema6d" as a keyword



Hybrid in vitro/in silico analysis of low‐affinity protein–protein interactions that regulate signal transduction by Sema6D

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recommendations! Published in 2022 at "Protein Science"

DOI: 10.1002/pro.4452

Abstract: Semaphorins constitute a large family of secreted and membrane‐bound proteins that signal through cell‐surface receptors, plexins. Semaphorins generally use low‐affinity protein–protein interactions to bind with their specific plexin(s) and regulate distinct cellular processes such as… read more here.

Keywords: sema6d; affinity; class; analysis ... See more keywords

SEMA6D Differentially Regulates Proliferation, Migration, and Invasion of Breast Cell Lines

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recommendations! Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c00840

Abstract: Semaphorin 6D (SEMA6D), a member of the class 6 semaphorin family, is a membrane-associated protein that plays a key role in the development of cardiac and neural tissues. A growing body of evidence suggests that… read more here.

Keywords: sema6d; cell; breast; expression ... See more keywords

Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer's disease.

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recommendations! Published in 2025 at "Science translational medicine"

DOI: 10.1126/scitranslmed.adx0027

Abstract: Cellular cross-talk, mediated by membrane receptors and their ligands, is crucial for brain homeostasis and can contribute to neurodegenerative diseases such as Alzheimer's disease (AD). To find cross-talk dysregulations involved in AD, we reconstructed cross-talk… read more here.

Keywords: disease; cross talk; cellular cross; talk ... See more keywords

SEMA6D, Negatively Regulated by miR-7, Contributes to C28/I2 chondrocyte's Catabolic and Anabolic Activities via p38 Signaling Pathway

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/9674221

Abstract: MiR-7 has been recognized as an osteoarthritis (OA-)-promoting factor, but the specific downstream pathway of miR-7 still remains unknown. Further investigation of the molecular regulatory mechanism of miR-7 might help develop a novel therapeutic method… read more here.

Keywords: sema6d; sema6d negatively; negatively regulated; regulated mir ... See more keywords