Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-1642
Abstract: Postpartum mammary gland involution is a tissue remodeling event that occurs in all mammals in the absence of nursing or after weaning to return the gland to the pre-pregnant state. The tissue microenvironment created by… read more here.
Keywords: sema7a; breast cancer; involution; gland ... See more keywords
Abstract 1284: The effect of Semaphorin 7A on breast cancer metastases and chemoresistance in young women
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1284
Abstract: Our overall goal is to understand drivers of chemoresistance in triple-negative breast cancer (TNBC) and the mechanisms that contribute to metastatic spread in young women. TNBC is more frequently diagnosed in women aged read more here.
Keywords: sema7a cells; breast cancer; young women; chemoresistance ... See more keywords
Vascular Semaphorin 7A Upregulation by Disturbed Flow Promotes Atherosclerosis Through Endothelial &bgr;1 Integrin
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DOI: 10.1161/atvbaha.117.310491
Abstract: Objective— Accumulating evidence suggests a role of semaphorins in vascular homeostasis. Here, we investigate the role of Sema7A (semaphorin 7A) in atherosclerosis and its underlying mechanism. Approach and Results— Using genetically engineered Sema7A−/−ApoE−/− mice, we… read more here.
Keywords: sema7a; adhesion; bgr integrin; apoe mice ... See more keywords
Endothelial semaphorin 7A promotes seawater aspiration-induced acute lung injury through plexin C1 and β1 integrin.
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DOI: 10.3892/mmr.2017.7097
Abstract: Inflammation and edema are two main characteristics in seawater aspiration‑induced acute lung injury (ALI). In a previous study of the authors, it was demonstrated that endothelial semaphorin 7A (SEMA7A) serves an important role in the… read more here.
Keywords: sema7a; plexin; seawater aspiration; aspiration induced ... See more keywords