Plate-Based Assay for Measuring Direct Semaphorin-Neuropilin Interactions.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6448-2_5
Abstract: The semaphorins are an essential family of axon guidance molecules that can be either secreted or are transmembrane proteins. Class 3 semaphorin (Sema3) family members are secreted and provide long-range guidance cues through two receptor… read more here.
Keywords: semaphorin; sema3 nrp; plate based; assay measuring ... See more keywords
Genetic inactivation of Semaphorin 3C protects mice from Acute Kidney Injury.
Sign Up to like & getrecommendations! Published in 2022 at "Kidney international"
DOI: 10.1016/j.kint.2021.12.028
Abstract: To guide the development of therapeutic interventions for acute kidney injury, elucidating the deleterious pathways of this global health problem is highly warranted. Emerging evidence has indicated a pivotal role of endothelial dysfunction in the… read more here.
Keywords: semaphorin; kidney injury; acute kidney; injury ... See more keywords
Decreased Expression of Semaphorin 3A and Semaphorin 7A Levels and Its Association with Systemic Lupus Erythematosus
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DOI: 10.1080/08820139.2019.1649280
Abstract: ABSTRACT A growing body of data suggests that semaphorins are involved in both normal and pathological immune responses, as well as autoimmune pathologies. To investigate the plasma semaphorin 3A (Sema3A) and semaphorin 7A (Sema7A) levels… read more here.
Keywords: significant differences; semaphorin; sema3a sema7a; sle ... See more keywords
Hippocampal semaphorin 3B improves depression‐like behaviours in mice by upregulating synaptic plasticity and inhibiting neuronal apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15680
Abstract: Depression is a global health problem, and there is a pressing need for a better understanding of its pathogenesis. Semaphorin 3B (Sema 3B) is an important axon guidance molecule that is primarily expressed in neurons… read more here.
Keywords: depression; sema; like behaviours; semaphorin ... See more keywords
Semaphorin 3F expression is reduced in pregnancy complicated by preeclampsia. An observational clinical study
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DOI: 10.1371/journal.pone.0174400
Abstract: Background and objective Preeclampsia is a systemic disorder, affecting 2–10% of pregnancies, characterized by a deregulated pro- and anti-angiogenic balance. Semaphorin 3F is an angiogenesis inhibitor. We aimed to investigate whether semaphorin 3F expression is… read more here.
Keywords: semaphorin expression; pregnancy; semaphorin; study ... See more keywords
Semaphorin 6D–expressing mesenchymal cells regulate IL-10 production by ILC2s in the lung
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DOI: 10.26508/lsa.202201486
Abstract: Group 2 innate lymphoid cells (ILC2s) have features specific to the niches in which they reside, and we found that semaphorin 6D signaling in the lung niche controls IL-10 production by ILC2s. Group 2 innate… read more here.
Keywords: lung; production; mesenchymal cells; semaphorin ... See more keywords
Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2018.00257
Abstract: Oxycodone is one a commonly used medication for pain, and is also a widely abused prescription opioid, like other short-acting MOPr agonists. Neurochemical and structural adaptations in brain following chronic MOPr-agonist administration are thought to… read more here.
Keywords: self administration; administration; semaphorin; axon guidance ... See more keywords