Elucidation of Metabolic and Disposition Pathways for Maribavir in Nonhuman Primates through Mass Balance and Semi–Physiologically Based Modeling Approaches
Sign Up to like & getrecommendations! Published in 2021 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.121.000493
Abstract: Maribavir is in phase 3 clinical development for treatment of cytomegalovirus infection/disease in transplant recipients. Previous research conducted using only intact cynomolgus monkeys indicated biliary secretion as the primary elimination pathway for maribavir and that… read more here.
Keywords: maribavir; mass balance; semi; physiologically based ... See more keywords