Cell Membrane Vesicle Camouflaged Artificial Cells
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202424504
Abstract: The integration of artificial and mammalian cells into semi‐synthetic aggregates remains a challenge in bottom‐up synthetic biology. Here, the fabrication of cell membrane vesicles (CMV) from HepG2 cells and their use as a coating for… read more here.
Keywords: cell membrane; synthetic aggregates; membrane vesicle; semi synthetic ... See more keywords
Hexahydrocannabinol and closely related semi-synthetic cannabinoids: A comprehensive review.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3519
Abstract: Since the early 2000s, there has been a turmoil on the global illicit cannabinoid market. Parallel to legislative changes in some jurisdictions regarding herbal cannabis, unregulated and cheap synthetic cannabinoids with astonishing structural diversity have… read more here.
Keywords: pharmacology; hemp; semi synthetic; hexahydrocannabinol closely ... See more keywords
From Kratom to Semi-Synthetic Opioids: The Rise and Risks of MGM-15.
Sign Up to like & getrecommendations! Published in 2025 at "Drug testing and analysis"
DOI: 10.1002/dta.3952
Abstract: Kratom (Mitragyna speciosa), a plant native to Southeast Asia, has long been used for its stimulant and analgesic properties. 7-Hydroxymitragynine (7-HMG) is a potent and selective opioid agonist in vitro and demonstrates a potent opioid effect… read more here.
Keywords: kratom; kratom semi; synthetic opioids; semi synthetic ... See more keywords
Hydrophilic interaction liquid chromatography-mass spectrometry as a new tool for the characterization of intact semi-synthetic glycoproteins.
Sign Up to like & getrecommendations! Published in 2017 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2017.05.020
Abstract: Improved methods for detailed characterization of complex glycoproteins are required in the growing sector of biopharmaceuticals. Hydrophilic interaction liquid chromatography (HILIC) coupled to high resolution (HR) time-of-flight mass spectrometric (TOF-MS) detection was examined for the… read more here.
Keywords: characterization intact; interaction liquid; semi synthetic; hydrophilic interaction ... See more keywords
A Semi-Synthetic Organism that Stores and Retrieves Increased Genetic Information
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature24659
Abstract: Since at least the last common ancestor of all life on Earth, genetic information has been stored in a four-letter alphabet that is propagated and retrieved by the formation of two base pairs. The central… read more here.
Keywords: information; semi synthetic; base; genetic information ... See more keywords
Investigating the role of the strong field ligands in [FeFe] hydrogenase: spectroscopic and functional characterization of a semi-synthetic mono-cyanide active site
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc02271k
Abstract: Artificial maturation of hydrogenases provides a path towards generating new semi-synthetic enzymes with novel catalytic properties. Here enzymes featuring a synthetic asymmetric mono-cyanide cofactor have been prepared using two different hydrogenase scaffolds. Their structure and… read more here.
Keywords: hydrogenase; semi synthetic; cyanide; mono cyanide ... See more keywords
Cytotoxic potential of dihydrochalcones from Eriosema glomeratum and their semi-synthetic derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2111563
Abstract: In the search of cytotoxic dihydrochalcones, this investigation led to the isolation of seven compounds (1-7) from Eriosema glomeratum and the preparation of eight derivatives (8-15). The cytotoxicity of samples was evaluated against lung (A549),… read more here.
Keywords: dihydrochalcones eriosema; potential dihydrochalcones; glomeratum semi; semi synthetic ... See more keywords
Analysing two‐dimensional effects in central loop transient electromagnetic sounding data using a semi‐synthetic tipper approach
Sign Up to like & getrecommendations! Published in 2018 at "Geophysical Prospecting"
DOI: 10.1111/1365-2478.12520
Abstract: We present a simple and feasible approach to analyse and identify two-dimensional effects in central loop transient electromagnetic sounding data and the correspondingly derived quasi two-dimensional conductivity models. The proposed strategy is particularly useful in… read more here.
Keywords: semi synthetic; tipper; two dimensional; transient electromagnetic ... See more keywords
The Effect of Antitumor Antibiotic Olivomycin A and Its New Semi-synthetic Derivative Olivamide on the Activity of Murine DNA Methyltransferase Dnmt3a
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297919010085
Abstract: Olivomycin A is a highly active antitumor drug that belongs to the family of aureolic acid antibiotics. The antitumor effect of olivomycin A is related to its ability to bind to the DNA minor groove… read more here.
Keywords: dna; semi synthetic; dna methyltransferase; antitumor ... See more keywords
Paclitaxel and its semi-synthetic derivatives: comprehensive insights into chemical structure, mechanisms of action, and anticancer properties
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Medical Research"
DOI: 10.1186/s40001-024-01657-2
Abstract: Cancer is a disease that can cause abnormal cell growth and can spread throughout the body. It is among the most significant causes of death worldwide, resulting in approx. 10 million deaths annually. Many synthetic… read more here.
Keywords: cancer; paclitaxel semi; anticancer; semi synthetic ... See more keywords
Novel substance, same old problems: admissions of psychosis precipitated by hexahydrocannabinol, a widely available semi-synthetic cannabinoid.
Sign Up to like & getrecommendations! Published in 2025 at "BJPsych bulletin"
DOI: 10.1192/bjb.2025.85
Abstract: AIMS AND METHOD To investigate the impact of the widespread availability and use of the semi-synthetic cannabinoid hexahydrocannabinol (HHC) on hospital admissions owing to psychosis. Medical records of patients admitted for psychotic illness to University… read more here.
Keywords: use; hexahydrocannabinol; semi synthetic; synthetic cannabinoid ... See more keywords