Semiconducting Polymer Nanoparticles with Surface‐Mimicking Protein Secondary Structure as Lysosome‐Targeting Chimaeras for Self‐Synergistic Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202203309
Abstract: Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive tumor microenvironment. The strategy that can efficiently activate cytotoxic T lymphocytes and inhibit… read more here.
Keywords: semiconducting polymer; immunotherapy; protein secondary; polymer nanoparticles ... See more keywords
Augmenting Immunogenic Cell Death and Alleviating Myeloid-Derived Suppressor Cells by Sono-Activatable Semiconducting Polymer Nanopartners for Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202302508
Abstract: Inducing immunogenic cell death (ICD) by sonodynamic therapy (SDT) is promising for cancer immunotherapy, which however is inefficient due to oxygen depletion that compromises SDT effect and mediates recruitment of immunosuppressive myeloid-derived suppressor cells (MDSCs).… read more here.
Keywords: cell death; semiconducting polymer; myeloid derived; polymer ... See more keywords
Recent Advances of Activatable Molecular Probes Based on Semiconducting Polymer Nanoparticles in Sensing and Imaging
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Science"
DOI: 10.1002/advs.201600481
Abstract: Molecular probes that change their signals in response to the target of interest have a critical role in fundamental biology and medicine. Semiconducting polymer nanoparticles (SPNs) have recently emerged as a new generation of purely… read more here.
Keywords: sensing imaging; semiconducting polymer; recent advances; activatable molecular ... See more keywords
Photoacoustic Imaging and Photothermal Therapy of Semiconducting Polymer Nanoparticles: Signal Amplification and Second Near-Infrared Construction.
Sign Up to like & getrecommendations! Published in 2021 at "Small"
DOI: 10.1002/smll.202004723
Abstract: Photoacoustic (PA) imaging and photothermal therapy (PTT) have attracted extensive attention in disease diagnosis and treatment. Although many exogenous contrast agents have been developed for PA imaging and PTT, the design guidelines to amplify their… read more here.
Keywords: imaging photothermal; semiconducting polymer; photoacoustic imaging; polymer nanoparticles ... See more keywords
Capsaicin-Decorated Semiconducting Polymer Nanoparticles for Light-Controlled Calcium-Overload/Photodynamic Combination Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200152
Abstract: Calcium-overload cancer therapy has gained more and more attention owing to its good therapeutic efficacy with low side effect. However, conventional calcium-overload therapy is achieved by introducing an additional calcium element into the tumor site… read more here.
Keywords: calcium; calcium overload; semiconducting polymer; therapy ... See more keywords
Near-infrared absorbing semiconducting polymer nanomedicines for cancer therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1865
Abstract: As a new type of organic optical nanomaterials, semiconducting polymer nanoparticles (SPNs) have the advantages of good optical characteristics and photostability, low toxicity concerns, and relatively simple preparation processes. Particularly, near-infrared (NIR) absorbing SPNs have… read more here.
Keywords: semiconducting polymer; near infrared; therapy; nanomedicines cancer ... See more keywords
Radioactive organic semiconducting polymer nanoparticles for multimodal cancer theranostics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2022.03.107
Abstract: Theranostics with integrations of both imaging and therapeutic elements can enable early diagnosis and effective treatment of cancer. Herein, we report the development of radioactive semiconducting polymer nanoparticles (rSPNs) for multimodal cancer theranostics. Such rSPNs… read more here.
Keywords: semiconducting polymer; cancer theranostics; cancer; polymer nanoparticles ... See more keywords
Ratiometric Fluorescent Detection of Intracellular Singlet Oxygen by Semiconducting Polymer Dots.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b04859
Abstract: Singlet oxygen (1O2) plays important roles in many biological processes. However, it is very difficult to detect 1O2 in the intracellular environment because of its relatively low concentration and short lifetime. Here, we developed a… read more here.
Keywords: polymer dots; detection; semiconducting polymer; singlet oxygen ... See more keywords
Soft Fiber Electronics Based on Semiconducting Polymer.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.2c00720
Abstract: Fibers, originating from nature and mastered by human, have woven their way throughout the entire history of human civilization. Recent developments in semiconducting polymer materials have further endowed fibers and textiles with various electronic functions,… read more here.
Keywords: semiconducting polymer; fiber electronics; soft fiber; medicine ... See more keywords
Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physical Chemistry C"
DOI: 10.1021/acs.jpcc.0c04983
Abstract: Semiconducting polymer nanoparticles (Pdots) are a promising fluorescent probe for a wide variety of bioanalytical applications, including as donors in energy transfer (ET)-based sensing and photod... read more here.
Keywords: energy transfer; transfer mechanism; semiconducting polymer; investigation energy ... See more keywords
Thermal Analysis of Semiconducting Polymer Crystals Free of a Mobile Amorphous Fraction
Sign Up to like & getrecommendations! Published in 2021 at "Macromolecules"
DOI: 10.1021/acs.macromol.0c02509
Abstract: Mobile-amorphous-free crystals of a semiconducting polymer, poly(3-hexyl thiophene) (P3HT), were made via a flow induced crystallization technique to yield crystals that were microns long while the... read more here.
Keywords: semiconducting polymer; polymer crystals; mobile amorphous; thermal analysis ... See more keywords