Semisynthesis of (-)-Bufospirostenin A Enabled by Photosantonin Rearrangement Reaction.
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DOI: 10.1021/jacs.1c12395
Abstract: An enantioselective semisynthesis of (-)-bufospirostenin A is described. The key steps in the synthesis involve use of our proposed biomimetic and diastereoselective photosantonin rearrangement reaction for construction of the 5/7 bicyclic motif, and a Co-catalyzed… read more here.
Keywords: reaction; semisynthesis bufospirostenin; photosantonin rearrangement; rearrangement reaction ... See more keywords