Cell-Cycle Modulation of Transcription Termination Factor Sen1
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cell"
DOI: 10.1016/j.molcel.2018.03.010
Abstract: Summary Many non-coding transcripts (ncRNA) generated by RNA polymerase II in S. cerevisiae are terminated by the Nrd1-Nab3-Sen1 complex. However, Sen1 helicase levels are surprisingly low compared with Nrd1 and Nab3, raising questions regarding how… read more here.
Keywords: transcription termination; sen1; termination; cell cycle ... See more keywords
Biochemical characterization of the helicase Sen1 provides new insights into the mechanisms of non-coding transcription termination
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkw1230
Abstract: Abstract Pervasive transcription is widespread and needs to be controlled in order to avoid interference with gene expression. In Saccharomyces cerevisiae, the highly conserved helicase Sen1 plays a key role in restricting pervasive transcription by… read more here.
Keywords: transcription; helicase sen1; non coding; sen1 ... See more keywords