Novel Recombinant Seneca Valley Virus Isolated from Slaughtered Pigs in Guangdong Province
Sign Up to like & getrecommendations! Published in 2019 at "Virologica Sinica"
DOI: 10.1007/s12250-019-00139-8
Abstract: Seneca valley virus (SVV) associated porcine idiopathic vesicular disease showed increasing geographic distribution in major pig-raising countries and it is important to monitor the epidemic strains. Here, two newly identified recombinant SVV strains, CH-GDFS-2018 and… read more here.
Keywords: slaughtered pigs; valley virus; isolated slaughtered; guangdong province ... See more keywords
Cholesterol-25-Hydroxylase Suppresses Seneca Valley Virus Infection via Producing 25-Hydroxycholesterol to Block Adsorption Procedure.
Sign Up to like & getrecommendations! Published in 2021 at "Virologica Sinica"
DOI: 10.1007/s12250-021-00377-9
Abstract: Cholesterol-25-hydroxylase (CH25H) is a membrane protein associated with endoplasmic reticulum, and it is an interferon-stimulated factor regulated by interferon. CH25H catalyzes cholesterol to produce 25-hydroxycholesterol (25HC) by adding a second hydroxyl to the 25th carbon… read more here.
Keywords: adsorption; ch25h; cholesterol; cholesterol hydroxylase ... See more keywords
Development of a novel real-time RT-PCR assay to detect Seneca Valley virus-1 associated with emerging cases of vesicular disease in pigs.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2016.10.012
Abstract: Seneca Valley virus 1 (SVV-1) can cause vesicular disease that is clinically indistinguishable from foot-and-mouth disease, vesicular stomatitis and swine vesicular disease. SVV-1-associated disease has been identified in pigs in several countries, namely USA, Canada,… read more here.
Keywords: real time; valley virus; disease; vesicular disease ... See more keywords
Immunogenicity and protective efficacy of an inactivated cell culture-derived Seneca Valley virus vaccine in pigs.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.12.055
Abstract: Seneca Valley virus (SVV) infection in pigs is associated with porcine idiopathic vesicular disease (PIVD). Outbreaks of SVV infection in pig herds have been reported in several Asia and Americas countries. Recently, a series of… read more here.
Keywords: vaccine; svv infection; seneca valley; virus ... See more keywords
Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.
Sign Up to like & getrecommendations! Published in 2019 at "Virology"
DOI: 10.1016/j.virol.2019.06.017
Abstract: Seneca Valley virus (SVV) is a member of the Picornaviridae family, which has been used to treat neuroendocrine cancer. The innate immune system plays an important role in SVV infection. However, few studies have elucidated… read more here.
Keywords: degradation; rig; degradation rig; valley virus ... See more keywords
Emergence of novel Seneca Valley virus strains in China, 2017
Sign Up to like & getrecommendations! Published in 2017 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.12662
Abstract: Since early 2017, several outbreaks of Seneca Valley virus (SVV) infection have re-emerged in China. We report the identification of novel SVV KS15-01-like strains showing a notable distinction with previous Chinese SVV strains. The determined… read more here.
Keywords: valley virus; novel seneca; seneca valley; emergence novel ... See more keywords
First report and genetic characterization of Seneca Valley virus (SVV) in Chile.
Sign Up to like & getrecommendations! Published in 2022 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.14747
Abstract: Seneca Valley virus (SVV) is a non-enveloped RNA virus and the only member of the Senecavirus A(SVA) species, in the Senecavirus genus, Picornaviridae family. SVV infection causes vesicular lesions in the oral cavity, snout, and… read more here.
Keywords: seneca valley; valley virus; virus svv; svv ... See more keywords
Seneca Valley Virus 3Cpro Mediates Cleavage and Redistribution of Nucleolin To Facilitate Viral Replication
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00304-22
Abstract: The nucleolus is a subnuclear cellular compartment, and nucleolin (NCL) resides predominantly in the nucleolus. NCL participates in viral replication, translation, internalization, and also serves as a receptor for virus entry. ABSTRACT Seneca Valley virus… read more here.
Keywords: cleavage; viral replication; seneca valley; replication ... See more keywords
Identification of a conserved neutralizing epitope in Seneca Valley virus VP2 protein: new insight for epitope vaccine designment
Sign Up to like & getrecommendations! Published in 2022 at "Virology Journal"
DOI: 10.1186/s12985-022-01791-5
Abstract: Background Seneca Valley virus (SVV) is a picornavirus that causes vesicular disease in swine. Clinical characteristics of the disease are similar to common viral diseases such as foot-and-mouth disease virus, porcine vesicular disease virus, and… read more here.
Keywords: vp2; seneca valley; epitope; virus ... See more keywords
Mfn2 is responsible for inhibition of the RIG-I/IRF7 pathway and activation of NLRP3 inflammasome in Seneca Valley virus-infected PK-15 cells to promote viral replication
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.955671
Abstract: Seneca Valley virus (SVV), a non-enveloped positive single-stranded virus can cause vesicular disease in swine. However, the mechanisms by which SVV activates an innate immune response remain unknown. Mitofusin-2 (MFN2), a mitochondria-shaping protein regulating mitochondrial… read more here.
Keywords: rig irf7; mfn2; seneca valley; virus ... See more keywords
Evolving role of seneca valley virus and its biomarker TEM8/ANTXR1 in cancer therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.930207
Abstract: Oncolytic viruses have made a significant inroad in cancer drug development. Numerous clinical trials are currently investigating oncolytic viruses both as single agents or in combination with various immunomodulators. Oncolytic viruses (OV) are an integral… read more here.
Keywords: tem8 antxr1; biomarker; valley virus; seneca valley ... See more keywords