The Cancer SENESCopedia: A delineation of cancer cell senescence
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.109441
Abstract: Summary Cellular senescence is characterized as a stable proliferation arrest that can be triggered by multiple stresses. Most knowledge about senescent cells is obtained from studies in primary cells. However, senescence features may be different… read more here.
Keywords: senescence; senescence cancer; cancer senescopedia; cancer cell ... See more keywords
The dynamic nature of senescence in cancer
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DOI: 10.1038/s41556-018-0249-2
Abstract: Cellular senescence is implicated in physiological and pathological processes spanning development, wound healing, age-related decline in organ functions and cancer. Here, we discuss cell-autonomous and non-cell-autonomous properties of senescence in the context of tumour formation… read more here.
Keywords: dynamic nature; senescence; biology; senescence cancer ... See more keywords
The Paradoxical Role of Cellular Senescence in Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.722205
Abstract: Cellular senescence occurs in proliferating cells as a consequence of various triggers including telomere shortening, DNA damage, and inappropriate expression of oncogenes. The senescent state is accompanied by failure to reenter the cell cycle under… read more here.
Keywords: senescence; senescence cancer; paradoxical role; cellular senescence ... See more keywords