p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells
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DOI: 10.3389/fimmu.2021.698565
Abstract: T-cell dysfunction arising upon repeated antigen exposure prevents effective immunity and immunotherapy. Using various clinically and physiologically relevant systems, we show that a prominent feature of PD-1-expressing exhausted T cells is the development of cellular… read more here.
Keywords: p16ink4a regulates; senescence expressing; senescence; cellular senescence ... See more keywords