Chronic Intermittent Hypoxia Triggers a Senescence-like Phenotype in Human White Preadipocytes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63761-7
Abstract: Obstructive sleep apnea (OSA) is a common sleep disorder associated with obesity. Emerging evidence suggest that OSA increases the risk of cardiovascular morbidity and mortality partly via accelerating the process of cellular aging. Thus, we… read more here.
Keywords: human white; senescence like; intermittent hypoxia; like phenotype ... See more keywords
RagC GTPase regulates mTOR to promote chemoresistance in senescence-like HepG2 cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.949737
Abstract: Radiotherapy and chemotherapy can arrest cancer cells in a senescence-like state, which can lead to therapy resistance and cancer relapse. mTOR is hyperactivated in senescent cells but the mechanisms remain unclear. In this study, we… read more here.
Keywords: hepg2 cells; senescence; senescence like; cancer ... See more keywords