Regulation of senescence and the SASP by the transcription factor C/EBPβ
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2019.110752
Abstract: Oncogene-induced senescence (OIS) serves as an important barrier to tumor progression in cells that have acquired activating mutations in RAS and other oncogenes. Senescent cells also produce a secretome known as the senescence-associated secretory phenotype… read more here.
Keywords: senescence sasp; senescence; sasp transcription; regulation senescence ... See more keywords
Cellular senescence and SASP in tumor progression and therapeutic opportunities
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DOI: 10.1186/s12943-024-02096-7
Abstract: Cellular senescence (CS), a permanent and irreversible arrest of the cell cycle and proliferation leading to the degeneration of cellular structure and function, has been implicated in various key physiological and pathological processes, particularly in… read more here.
Keywords: senescence; cellular senescence; tumor progression; tumor ... See more keywords
Senescence and SASP Are Potential Therapeutic Targets for Ischemic Stroke
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DOI: 10.3390/ph17030312
Abstract: Aging is a known co-morbidity of ischemic stroke with its risk and severity increasing every year past 55+. While many of the current stroke therapies have shown success in reducing mortality, post-stroke morbidity has not… read more here.
Keywords: senescence; ischemic stroke; stroke; sasp potential ... See more keywords