Role of senescent fibroblasts in the development of idiopathic guttate hypomelanosis
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Dermatology"
DOI: 10.1111/bjd.18801
Abstract: BACKGROUND Idiopathic guttate hypomelanosis (IGH) is a common hypopigmentary disorder occurring mainly on exposed areas in elderly individuals. Long-term sun exposure is thought to be a main cause of IGH but the pathogenesis is still… read more here.
Keywords: guttate hypomelanosis; senescent; idiopathic guttate; senescent fibroblasts ... See more keywords
Abstract 2518: Heterogeneity of cytokine secretion in single senescent fibroblasts is impacted by ONC201 and ABT-263
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2518
Abstract: Cellular senescence and the associated secretory phenotype (SASP) promote cancer. During the process of aging, cellular and molecular changes that occur in non-cancerous cells can alter responses to cancer therapy and immune response in the… read more here.
Keywords: abt 263; senescent; senescent fibroblasts; cancer ... See more keywords
Fibroblast Senescence in Idiopathic Pulmonary Fibrosis
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DOI: 10.3389/fcell.2020.593283
Abstract: Aging is an inevitable and complex natural phenomenon due to the increase in age. Cellular senescence means a non-proliferative but viable cellular physiological state. It is the basis of aging, and it exists in the… read more here.
Keywords: idiopathic pulmonary; senescence; pulmonary fibrosis; ipf ... See more keywords
GALC Triggers Tumorigenicity of Colorectal Cancer via Senescent Fibroblasts
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DOI: 10.3389/fonc.2020.00380
Abstract: Colorectal cancer (CRC)-associated senescent fibroblasts may play a crucial role in tumor progression, but the mechanism remains unclear. In order to solve this complicated problem, we randomly collected 16 patients with CRC, who had been… read more here.
Keywords: colorectal cancer; expression; crc; cell ... See more keywords