Nucleus distribution of cathepsin B in senescent microglia promotes brain aging through degradation of sirtuins
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DOI: 10.1016/j.neurobiolaging.2020.09.001
Abstract: Cathepsin B (CatB) leakage from the lysosome into the cytosol in senescent microglia is associated with cognitive impairment. However, whether cellular compartmental translocation of CatB is associated with brain aging remains unclear. In the present… read more here.
Keywords: catb; cathepsin; senescent microglia; brain aging ... See more keywords