Soluble endoglin modulates the pro‐inflammatory mediators NF‐&kgr;B and IL‐6 in cultured human endothelial cells
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.03.014
Abstract: Aims: Endoglin is a transmembrane glycoprotein, that plays an important role in regulating endothelium. Proteolytic cleavage of membrane endoglin releases soluble endoglin (sEng), whose increased plasma levels have been detected in diseases related to the… read more here.
Keywords: endoglin modulates; seng; endothelial cells; soluble endoglin ... See more keywords
New highly sensitive sandwich ELISA system for soluble endoglin quantification in different biological fluids
Sign Up to like & getrecommendations! Published in 2018 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2018.1516892
Abstract: Abstract Soluble endoglin (sEng) is a fragment of a membrane-associated receptor (CD105) expressed on endothelial cells, mesenchymal stem cells and trophoblast cells. It is considered as a regulatory factor involved in the development of preeclampsia… read more here.
Keywords: new elisa; sandwich elisa; seng; soluble endoglin ... See more keywords
Serial measurement of soluble endoglin for risk assessment at the diagnosis of fetal growth restriction.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of clinical practice"
DOI: 10.1111/ijcp.14840
Abstract: AIM In this study, we aimed to investigate the soluble endoglin (sEng) levels in the pregnant women with fetal growth restriction (FGR) and to examine the possible relation of the sEng levels with the time… read more here.
Keywords: growth restriction; pregnant women; seng; seng levels ... See more keywords
Prognostic value of soluble endoglin in patients with septic shock and severe COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.972040
Abstract: Sepsis is a clinical syndrome characterized by a dysregulated response to infection. It represents a leading cause of mortality in ICU patients worldwide. Although sepsis is in the point of interest of research for several… read more here.
Keywords: severe covid; soluble endoglin; septic shock; seng ... See more keywords
Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1116422
Abstract: Labetalol is used for the therapy of hypertension in preeclampsia. Preeclampsia is characterized by high soluble endoglin (sEng) concentration in plasma and coincides with intrahepatic cholestasis during pregnancy (ICP), which threatens the fetus with the… read more here.
Keywords: labetalol; seng; plasma; mice ... See more keywords
The Association of IL-17 and PlGF/sENG Ratio in Pre-Eclampsia and Adverse Pregnancy Outcomes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph20010768
Abstract: The aim of the study was to assess the role of concentrations of interleukin-17 (IL-17), placental growth factor (PlGF) and soluble endoglin (sENG), as well as the PlGF/sENG ratio in pregnancy complicated by pre-eclampsia (PE)… read more here.
Keywords: seng; pregnancy; pre eclampsia; seng ratio ... See more keywords
Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21239021
Abstract: Nonalcoholic steatohepatitis (NASH) is characterized by hepatic steatosis with inflammation and fibrosis. Membrane endoglin (Eng) expression is shown to participate in fibrosis, and plasma concentrations of soluble endoglin (sEng) are increased in patients with hypercholesterolemia… read more here.
Keywords: nonalcoholic steatohepatitis; cholesterol; steatohepatitis nash; seng ... See more keywords
Soluble Endoglin Stimulates Inflammatory and Angiogenic Responses in Microglia That Are Associated with Endothelial Dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031225
Abstract: Increased soluble endoglin (sENG) has been observed in human brain arteriovenous malformations (bAVMs). In addition, the overexpression of sENG in concurrence with vascular endothelial growth factor (VEGF)-A has been shown to induce dysplastic vessel formation… read more here.
Keywords: stimulates inflammatory; seng; dysfunction; endoglin stimulates ... See more keywords